https://stream.echo6.co/videos/watch/009880cc-472b-42c5-9e4c-172dd4e03970 Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In Part 1 of our two-part series on Fatty Acid Oxidation, Professor Zach Murphy guides you through the essential early steps that prepare fatty acids for energy production through mitochondrial β-oxidation. This lecture focuses on fatty acids' transport, activation, and mitochondrial entry, setting the stage for their breakdown into usable energy. We begin by discussing how fatty acids are mobilized from adipose tissue and carried through the bloodstream bound to albumin. Once inside cells, fatty acids are activated into fatty acyl-CoA by acyl-CoA synthetase in the cytoplasm. From there, we explain the critical carnitine shuttle system—including CPT-1, translocase, and CPT-2—that allows long-chain fatty acids to enter the mitochondrial matrix for oxidation. The lecture also introduces the four repeating steps of β-oxidation: Oxidation by acyl-CoA dehydrogenase, Hydration by enoyl-CoA hydratase, Oxidation by hydroxyacyl-CoA dehydrogenase, Thiolytic cleavage by β-ketothiolase, Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #FattyAcidOxidation #Metabolism Wed, 15 Apr 2026 11:48:27 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/009880cc-472b-42c5-9e4c-172dd4e03970 All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.