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        <title>Hepatitis B | Clinical Medicine</title>
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        <description>Premium Member Resources: https://ninjanerd.org Ninja Nerds! In this lecture, Professor Zach Murphy breaks down Hepatitis B with a clear, high-yield approach focused on recognition, diagnosis, and management. This video builds a practical framework for understanding how Hepatitis B presents as both an acute and chronic infection and why it is one of the most clinically important viral hepatitides. We begin with epidemiology and transmission, emphasizing bloodborne, sexual, and perinatal spread. Zach then walks through the pathophysiology, highlighting how the virus interacts with the immune system, leading to acute inflammation, potential chronic infection, and long-term complications. Next, the lecture covers the clinical presentation and diagnosis, focusing on acute Hepatitis B symptoms, including fatigue, jaundice, and the classic immune-complex findings such as rash and arthralgias. You will learn the stepwise diagnostic approach using the Hepatitis B serology panel and how to interpret key markers to distinguish acute, chronic, and resolved infection. The session then focuses on chronic Hepatitis B, including disease progression, risk of cirrhosis and hepatocellular carcinoma, and how to assess viral activity and infectivity using additional markers. Finally, Zach reviews management and prevention, including indications for antiviral therapy, long-term monitoring, vaccination, and post-exposure prophylaxis. Enjoy the lecture, and please support us below! Table of Contents: 0:00 Lab 0:19 Etiology, Transmission and Pathophysiology of Hepatitis B 10:54 HDV Infection 29:57 Classic Findings of Prodrome 42:20 Classic Findings of Icteric Phase 48:04 Chronic Hepatitis B 51:00 Cirrhosis 54:56 Hepatocellular Carcinoma A 58:07 Acute Liver Failure 1:02:30 Extra Hepatic Manifestations 1:08:04 Diagnostic Approach to Hepatitis B 1:22:14 Treatment of Hepatitis B 1:28:16 Prevention of Hepatitis B 1:31:25 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #infectiousdisease #hepatitisB</description>
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