https://stream.echo6.co/videos/watch/3de233ae-79ec-44e4-89d5-63c2837e1741 Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this hematology and physiology lecture, Professor Zach Murphy presents a clear and high-yield breakdown of the Coagulation Cascade, a critical component of hemostasis that helps prevent excessive bleeding following vascular injury. We begin with an overview of hemostasis, including the vascular spasm, platelet plug formation, and the activation of the coagulation cascade. The lecture focuses on the two primary pathways—intrinsic and extrinsic—and how they converge at the common pathway to ultimately generate thrombin, which converts fibrinogen to fibrin, stabilizing the clot. You’ll learn the sequence and roles of key clotting factors, the importance of calcium and phospholipids, and how laboratory tests like PT, aPTT, and INR correspond to different parts of the cascade. We also explore the role of Vitamin K, factor XIII, and clinical correlations such as hemophilia, liver disease, and disseminated intravascular coagulation (DIC). This lecture simplifies a complex system into a logical and visual process, helping you connect the biochemistry of coagulation with clinical practice. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #Hemostasis #coagulationcascade Wed, 15 Apr 2026 13:29:32 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/3de233ae-79ec-44e4-89d5-63c2837e1741 All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.