https://stream.echo6.co/videos/watch/4f67d877-1f18-4662-9754-fcef29dec78b Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this endocrine physiology lecture, Professor Zach Murphy provides a comprehensive breakdown of Antidiuretic Hormone (ADH), also known as vasopressin, emphasizing its crucial role in water balance, vascular tone, and homeostatic regulation. We begin by discussing ADH’s synthesis in the supraoptic nucleus of the hypothalamus and its release from the posterior pituitary in response to changes in plasma osmolality and blood volume. This lecture highlights the two major ADH receptor pathways—V2 receptors in the renal collecting ducts, which promote water reabsorption via aquaporin-2 channels, and V1 receptors in vascular smooth muscle, which mediate vasoconstriction. You’ll also learn the physiologic triggers for ADH release, including increased serum osmolality, hypovolemia, and angiotensin II, as well as the inhibitory effects of alcohol and conditions that impair feedback control. We tie in clinical relevance by exploring disorders such as diabetes insipidus (central and nephrogenic) and SIADH, highlighting diagnostic features and treatment strategies. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #AntidiureticHormone #ADH Wed, 15 Apr 2026 09:54:55 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/4f67d877-1f18-4662-9754-fcef29dec78b All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.