https://stream.echo6.co/videos/watch/5e960efc-4044-4d41-ba72-7bc33734b980 Premium Member Resources: https://ninjanerd.org Ninja Nerds! In this lecture, Professor Zach Murphy breaks down Hepatitis A with a clear, high-yield approach focused on recognition, diagnosis, and management. This video builds a practical framework for understanding how Hepatitis A is transmitted, why it causes acute liver injury, and how to quickly identify it in clinical scenarios. We begin with epidemiology and transmission, emphasizing the fecal-oral route via contaminated food, water, and close contact. Zach then walks through the pathophysiology, highlighting the immune-mediated hepatocyte injury that leads to the classic two-phase presentation. Next, the lecture covers clinical presentation, focusing on the progression from a prodrome of fever, fatigue, nausea, and myalgias to the icteric phase with jaundice, dark urine, and right upper quadrant discomfort. You will learn how to recognize the hepatocellular injury pattern on labs and confirm the diagnosis using Hepatitis A serologies. The session then focuses on diagnostic strategy and management, including when to order imaging to rule out biliary obstruction, how to assess for liver dysfunction, and the principles of supportive care. Special attention is given to identifying patients at risk for acute liver failure and when escalation of care is required. Finally, Zach reviews prevention, including vaccination, post-exposure prophylaxis, and key public health considerations. Enjoy the lecture, and please support us below! Table of Contents: 0:00 Lab 0:51 Etiology, Transmission and Pathophysiology 27:04 Classic Findings of Prodromal Phase 37:20 Classic Findings of Icteric Phase 48:41 Acute Liver Failure 56:00 Diagnostic Approach to Hepatitis A 1:03:34 Prevention of Hepatitis A 1:08:18 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #infectiousdiseases #hepatitisA Wed, 10 Jun 2026 10:01:34 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/5e960efc-4044-4d41-ba72-7bc33734b980 All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.