https://stream.echo6.co/videos/watch/631e5532-0bb0-4f9e-8d25-8f3757ea211e Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this cardiovascular pharmacology lecture, Professor Zach Murphy provides a high-yield breakdown of ACE Inhibitors (ACE-Is) and Angiotensin Receptor Blockers (ARBs)—two cornerstone drug classes used in the treatment of hypertension, heart failure, diabetic nephropathy, and post-myocardial infarction care. We begin by reviewing the Renin-Angiotensin-Aldosterone System (RAAS) and how it regulates blood pressure, fluid balance, and vascular resistance. You’ll learn how ACE inhibitors (e.g., Lisinopril, Enalapril, Ramipril) block the conversion of angiotensin I to angiotensin II, leading to vasodilation, reduced aldosterone, and decreased afterload and preload. We then cover ARBs (e.g., Losartan, Valsartan, Candesartan), which selectively block the angiotensin II type 1 receptor (AT₁), offering similar benefits with a lower risk of bradykinin-related side effects such as cough and angioedema. The lecture highlights therapeutic uses, contraindications (e.g., pregnancy, bilateral renal artery stenosis), and adverse effects including hyperkalemia, hypotension, and renal function changes. You’ll also learn key clinical distinctions between ACE-Is and ARBs and when to choose one over the other. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #ACEinhibitors #ARBs Wed, 15 Apr 2026 17:18:36 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/631e5532-0bb0-4f9e-8d25-8f3757ea211e All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.