https://stream.echo6.co/videos/watch/6d29e1c6-3879-42a2-90a6-78e0aa909fff Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this hematology lecture, Professor Zach Murphy presents a focused and high-yield breakdown of Polycythemias, explaining the causes, classification, and clinical relevance of elevated red blood cell mass. We begin by defining polycythemia and reviewing how it’s identified through increased hematocrit and hemoglobin levels. The lecture then distinguishes between relative polycythemia, caused by plasma volume contraction (e.g., dehydration), and absolute polycythemia, characterized by a true increase in red blood cell production. We explore the two major types of absolute polycythemia: • Primary polycythemia (Polycythemia Vera): A myeloproliferative neoplasm driven by JAK2 mutations, with symptoms such as aquagenic pruritus, thrombosis, and splenomegaly. • Secondary polycythemia: Caused by elevated erythropoietin (EPO) levels due to chronic hypoxia (e.g., COPD, high altitude), EPO-secreting tumors, or conditions like sleep apnea. You’ll also learn how to differentiate these types using EPO levels, oxygen saturation, and JAK2 mutation testing, and how treatment strategies vary depending on the underlying cause. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #Polycythemias #Hematology Mon, 13 Apr 2026 11:50:34 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/6d29e1c6-3879-42a2-90a6-78e0aa909fff All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.