https://stream.echo6.co/videos/watch/946d3dc6-bad2-457b-95d0-98f47002d1ac Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this cardiovascular pharmacology lecture, Professor Zach Murphy delivers a clear and high-yield breakdown of Calcium Channel Blockers (CCBs), focusing on their mechanisms, classifications, clinical uses, and side effect profiles. We begin by reviewing how CCBs inhibit L-type voltage-gated calcium channels, reducing calcium influx into vascular smooth muscle and cardiac myocytes. This leads to vasodilation, decreased myocardial contractility, and slowed conduction through the AV node, depending on the drug class. The lecture divides CCBs into two major categories: • Dihydropyridines (e.g., Amlodipine, Nifedipine, Felodipine) – Act primarily on vascular smooth muscle to reduce systemic vascular resistance, making them ideal for treating hypertension and vasospastic angina • Non-dihydropyridines (Verapamil, Diltiazem) – Affect both the heart and blood vessels, useful for rate control in atrial fibrillation, angina, and hypertension, with negative chronotropic and inotropic effects We also compare side effects: peripheral edema, reflex tachycardia, constipation (notably with Verapamil), bradycardia, and potential AV block. Clinical cautions and drug interactions are emphasized, especially when combining with beta blockers. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #CalciumChannelBlockers #Antihypertensives Wed, 15 Apr 2026 15:36:37 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/946d3dc6-bad2-457b-95d0-98f47002d1ac All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.