https://stream.echo6.co/videos/watch/a36b4df4-8c0c-4182-96b2-de730b36d955 Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In Part 2 of our Fatty Acid Oxidation series, Professor Zach Murphy concludes this essential metabolic pathway by focusing on the ATP yield generated from the complete oxidation of long-chain fatty acids. This lecture helps you synthesize everything you’ve learned by calculating net energy production and addressing common points of confusion in β-oxidation. We begin by reviewing how repeated cycles of β-oxidation produce NADH, FADH₂, and acetyl-CoA, which feed into the electron transport chain and TCA cycle to generate ATP. A key focus of this lecture is the energy balance from a 16-carbon fatty acid, palmitoleic acid, with two different ATP yield models: • 1:52: ATP is hydrolyzed to AMP + Pi during activation. • 13:52: We subtract 2 ATP for activation cost. • Using the traditional model (NADH = 3 ATP, FADH₂ = 2 ATP), the net ATP yield is 129 ATP. • Using the modern model (NADH = 2.5 ATP, FADH₂ = 1.5 ATP), the net ATP yield is 106 ATP. This lecture clarifies these calculations and reinforces why understanding activation cost, cofactor yield, and ATP conversion models is critical for accurately interpreting β-oxidation energetics. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #FattyAcidOxidation #Metabolism Wed, 15 Apr 2026 15:48:46 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/a36b4df4-8c0c-4182-96b2-de730b36d955 All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.