https://stream.echo6.co/videos/watch/a88d7e3e-b5fb-4a2a-b0cb-c74cbc5191af Premium Member Resources: https://ninjanerd.org Ninja Nerds! In this lecture, Professor Zach Murphy breaks down COVID-19 with a clear, high-yield approach focused on recognition, diagnosis, and management. This video builds a practical framework for understanding how SARS-CoV-2 causes disease and why severity can range from mild upper respiratory symptoms to respiratory failure and multiorgan dysfunction. We begin with virology and pathophysiology, including the role of the spike protein, angiotensin-converting enzyme 2 receptor binding, and mechanisms driving viral replication, lung injury, inflammation, and hypercoagulability. Next, the lecture covers clinical presentation and severity classification. You will learn to recognize common symptoms, identify high-risk patients, and distinguish mild, moderate, severe, and critical disease based on oxygenation, imaging, and organ involvement. The session then focuses on diagnosis and complications, including appropriate testing strategies, laboratory and imaging findings, and major complications such as acute respiratory distress syndrome, thrombosis, acute kidney injury, and cardiac involvement. Finally, Zach reviews treatment and prevention, including outpatient antivirals for high-risk patients, inpatient management for severe and critical illness, and key vaccination principles. Enjoy the lecture, and please support us below! Table of Contents: 0:00 Lab 0:44 Etiology of COVID-19 12:24 Risk Factors for Severe/Critical COVID-19 22:09 Pathophysiology of COVID-19 1:16:47 Classic Findings of COVID-19 1:22:04 Complications of COVID-19 1:29:43 Diagnostic Approach to COVID-19 1:40:15 Complication Workup for COVID-19 1:44:33 Treatment of COVID-19 1:59:27 Treatment Approach to COVID-19 2:05:01 Prevention of COVID-19 2:08:04 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media https://www.tiktok.com/@ninjanerdlectures https://www.instagram.com/ninjanerdlectures https://www.facebook.com/ninjanerdlectures https://x.com/ninjanerdsci/ https://www.linkedin.com/company/ninja-nerd/ 💬 Join Our Community Discord: https://discord.gg/3srTG4dngW #ninjanerd #infectiousdiseases #covid19 Wed, 13 May 2026 15:50:04 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://stream.echo6.co https://stream.echo6.co/client/assets/images/icons/icon-512x512.png https://stream.echo6.co/videos/watch/a88d7e3e-b5fb-4a2a-b0cb-c74cbc5191af All rights reserved, unless otherwise specified in the terms specified at https://stream.echo6.co/about and potential licenses granted by each content's rightholder.